邱琇团队:孕期抑郁或与饮食模式存在关联
创作:Epi汪 审核:Epi汪 01月08日
  • 纳入广州出生队列研究中17430名孕妇,对其孕中期饮食情况进行调查,并通过聚类分析,归纳出6种饮食模式;
  • 分别包括多样型、蔬菜型、肉型、谷物型、牛奶型和水果型;
  • 在孕早期和晚期,分别有19.3%和15.7%的孕妇报告有抑郁症状;
  • 与“多样型”饮食模式相比,除“谷物型”外的其他4种饮食模式的孕妇抑郁评分均更低,其中蔬菜、牛奶和水果型饮食模式的孕妇抑郁风险降低显著;
  • 健康饮食评分表明,蔬菜、水果和牛奶型饮食更健康。
主编推荐语
Epi汪
既往的孕期饮食研究更多关注如何补充足够的营养,但是越来越多的研究发现膳食结构或许会影响心理健康。邱琇团队通过对广州出生队列数据的分析发现,孕期女性的饮食结构中更多的蔬菜、水果、坚果和乳制品与抑郁症状的评分呈负相关。本研究为孕期保健指导提供了重要的参考依据。
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Clinical Nutrition [IF:7.324]

Maternal dietary patterns and depressive symptoms during pregnancy: The Born in Guangzhou Cohort Study

母亲饮食模式与孕期抑郁症状的关联:广州出生队列研究

10.1016/j.clnu.2020.11.038

2020-12-07, Article

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Maternal dietary patterns and depressive symptoms during pregnancy: The Born in Guangzhou Cohort Study: Maternal depression has been reported to be harmful to maternal and child health, and nutrition-mental health interactions may play a key role, but evidence from longitudinal studies throughout pregnancy remains insufficient. This study aimed to investigate the association of maternal dietary patterns with depressive symptoms throughout pregnancy.
Methods: This study was based in the Born in Guangzhou Cohort Study. Dietary patterns were defined by cluster analysis based on validated food frequency questionnaires in mid-pregnancy. A healthy diet score was also developed based on predefined criteria of existing dietary guidelines. Depressive symptoms were measured by Self-rating Depression Scale (SDS) in both early and late pregnancy, with SDS scores ≥53 defined as having depressive symptoms. Associations of dietary patterns with SDS scores were examined by linear-mixed models; associations of dietary patterns with the odds of having depressive symptoms were examined by mixed-effects logistic models. The associations of the healthy diet score with both dietary patterns and depressive symptoms were also explored.
Results: Six dietary patterns were identified in 17,430 pregnant women, namely ‘Varied’ (n = 3902, 22.4%), ‘Vegetables’ (n = 3269, 18.8%), ‘Meats’ (n = 2951, 16.9%), ‘Cereals’ (n = 2719, 15.6%), ‘Milk’ (n = 2377, 13.6%), and ‘Fruits’ (n = 2212, 12.7%). There were 19.3% and 15.7% of participants with depressive symptoms in early and late pregnancy, respectively. Compared with the ‘Varied’ pattern, all other patterns were associated with lower SDS scores during pregnancy except for ‘Cereals’ (‘Vegetables’: adjusted β [aβ] −0.78, 95% CI −1.16, −0.40; ‘Meats’: aβ −0.48, 95% CI −0.87, −0.09; ‘Milk’: aβ −0.52, 95% CI −0.94, −0.10; ‘Fruits’: aβ −0.85, 95% CI −1.27, −0.42). The ‘Vegetables’ (adjusted OR [aOR] 0.79, 95% CI 0.67, 0.93), ‘Milk’ (aOR 0.76, 95% CI 0.63, 0.91), and ‘Fruits’ (aOR 0.77, 95% CI 0.64, 0.93) patterns were associated with lower odds of having depressive symptoms during pregnancy than the ‘Varied’ pattern. Results for the healthy diet score revealed the healthiness of the ‘Vegetables’, ‘Fruits’, and ‘Milk’ patterns and supported an inverse association between healthy dietary patterns and depressive symptoms throughout pregnancy.
Conclusions: Diets rich in vegetables, fruits, nuts, and dairy products had an inverse association with depressive symptoms throughout pregnancy. Our findings add support to the existing dietary guidelines that healthy diets might also have potential benefits to maternal mental health.

First Authors:
Peiyuan Huang

Correspondence Authors:
Xiu Qiu

All Authors:
Peiyuan Huang,Dongmei Wei,Wanqing Xiao,Mingyang Yuan,Niannian Chen,Xueling Wei,Junyi Xie,Jinhua Lu,Xiaoyan Xia,Minshan Lu,Songying Shen,Jianrong He,Xiu Qiu

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