极低卡路里饮食+行为治疗+低强度锻炼可缓解抑郁症状(综述)
创作:szx 审核:szx 2018年12月13日
  • 纳入9项研究进行荟萃分析,以及11项研究进行系统性综述,研究极低卡路里饮食(VLCD)对主观抑郁症状及焦虑的影响;
  • 在进行8-16周的饮食干预的同时,采取行为治疗及低强度的体育锻炼,可显著缓解抑郁症状;
  • 若进行1-7周的饮食干预,同时不采取行为治疗及体育锻炼,则对抑郁症状无显著改善;
  • 饮食干预对焦虑无显著影响;
  • 在使用VLCD治疗抑郁症时,需注意至少进行8周的饮食干预,并同时采取行为治疗及低强度锻炼。
主编推荐语
szx
International Journal of Obesity上发表的一项荟萃分析结果,发现8-16周的极低卡路里饮食干预,辅以行为治疗及低强度锻炼,可显著缓解主观抑郁症状,但对焦虑无显著影响。
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The effect of a very low calorie diet on subjective depressive symptoms and anxiety: meta-analysis and systematic review

极低卡路里饮食对主观抑郁症状及焦虑的影响:荟萃分析与系统性综述

10.1038/s41366-018-0245-4

2018-11-23, Review

Abstract & Authors:展开

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There are conflicting findings regarding the effect very low calorie diets (VLCDs) have on self-reported depressive symptoms and anxiety levels. Some studies have reported decreased subjective depressive symptoms and anxiety post-diet, whereas other studies have not. Further complicating matters, the protocol for VLCDs vary substantially across studies, which could account for the mixed findings. The primary goal of this meta-analysis and systematic review was to determine the effect VLCDs have on subjective depressive symptoms and anxiety pre- to post-diet. In addition, potential moderators (the presence/absence of behavioral therapy, duration of diet, inclusion/exclusion of low intensity exercise, and amount of weight lost) were examined to assess the effect of procedural deviations across VLCD studies on depressive symptoms and anxiety. A random-effects model was used for the meta-analysis and included nine studies with 16 independent samples. To further explain the results, study rigor was examined in the systematic review, which included 11 studies with 20 independent samples. Depressive symptoms significantly decreased pre- to post-diet when behavioral therapy was implemented during the diet, the duration of the diet was relatively long (8-16 weeks), low intensity exercise was included, and the dieters lost 14.1 kg or more post-diet. However, no difference in depressive symptoms were observed pre- to post-diet when behavioral therapy was not included, the diet was shorter (1-7 weeks), no exercise was implemented and dieters lost <14 kg of weight post-diet. There was no change in anxiety pre- to post-diet. Health care providers involved in supervising VLCDs should consider using a VLCD of at least 8 weeks that includes behavioral therapy and low intensity exercise in order to enhance the potential benefits of VLCDs on depressive symptoms. More research is required to examine the effect of VLCDs on anxiety.

First Authors:
Natalie Ein

Correspondence Authors:
Kristin Vickers

All Authors:
Natalie Ein,Bonnie Armstrong,Kristin Vickers

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