国内团队:低GI饮食有助于控制血糖
创作:大力 审核:mildbreeze 2019年08月11日
  • 纳入了54项针对糖耐量受损、1型或2型糖尿病的成人或儿童的随机对照试验;
  • 低升糖指数(GI)饮食能有效降低糖化血红蛋白(HbA1c)、空腹血糖、BMI、总胆固醇和低密度脂蛋白,但对空腹胰岛素、胰岛素抵抗指数(HOMA-IR)、高密度脂蛋白、甘油三酯或胰岛素需求没有影响;
  • 空腹血糖和HbA1c的降低与体重呈负相关;
  • 在持续时间最长的研究中,空腹血糖下降幅度最大;
  • 低GI饮食或有助于控制血糖,降低糖尿病前期或糖尿病患者的体重。
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mildbreeze
有不少临床研究探索了不同饮食干预对糖尿病的改善作用,American Journal of Clinical Nutrition近期发表一篇来自华中科技大学同济医学院协和医院孙璐璐团队的研究,对54临床试验进行荟萃分析,对比低升糖指数(GI)饮食与其它饮食(如:碳水化合物替代饮食、高脂饮食、高纤维饮食、高GI饮食、低脂饮食等)在控制糖尿病和糖耐受损患者的血糖、体重和血脂等方面的效果差异,表明低GI饮食在控制血糖方面的效果优于其它饮食干预。
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Low-glycemic index diets as an intervention for diabetes: a systematic review and meta-analysis

低升血糖指数饮食作为糖尿病的干预手段:系统回顾和荟萃分析

10.1093/ajcn/nqz149

2019-08-02, Review

Abstract & Authors:展开

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Background: Low-glycemic index (GI) diets are thought to reduce postprandial glycemia, resulting in more stable blood glucose concentrations.
Objective: We hypothesized that low-GI diets would be superior to other diet types in lowering measures of blood glucose control in people with type 1 or type 2 diabetes, or impaired glucose tolerance.
Methods: We searched PubMed, the Cochrane Library, EMBASE, and clinical trials registries for published and unpublished studies up until 1 March, 2019. We included 54 randomized controlled trials in adults or children with impaired glucose tolerance, type 1 diabetes, or type 2 diabetes. Continuous data were synthesized using a random effects, inverse variance model, and presented as standardized mean differences with 95% CIs.
Results: Low-GI diets were effective at reducing glycated hemoglobin (HbA1c), fasting glucose, BMI, total cholesterol, and LDL, but had no effect on fasting insulin, HOMA-IR, HDL, triglycerides, or insulin requirements. The reduction in fasting glucose and HbA1c was inversely correlated with body weight. The greatest reduction in fasting blood glucose was seen in the studies of the longest duration.
Conclusions: Low-GI diets may be useful for glycemic control and may reduce body weight in people with prediabetes or diabetes.

First Authors:
Mohammad Ishraq Zafar

Correspondence Authors:
Lu-Lu Chen

All Authors:
Mohammad Ishraq Zafar,Kerry E Mills,Juan Zheng,Anita Regmi,Sheng Qing Hu,Luoning Gou,Lu-Lu Chen

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