多吃鱼或可降低心血管疾病等慢性病的风险(综述)
  • 共纳入34项前瞻性队列研究的荟萃分析,汇总了从298项主要前瞻性队列研究中获得的40种不同结局的相对风险,用来评估鱼类摄入与慢性病风险之间的关联;
  • 中等质量的证据表明,每日鱼类摄入量每增加100g,与全因死亡率及心血管疾病死亡率的降低相关,并与冠心病、心肌梗塞、中风、心力衰竭、抑郁症和肝癌的发病风险降低相关;
  • 鱼类摄入与大多数部位的癌症没有明显的关联,证据的质量被评为低和非常低。
主编推荐语
szx
鱼类是膳食长链多不饱和脂肪酸EPA和DHA的主要来源,被认为是保护心血管最好的食物之一。Advances in Nutrition 近期发表了一篇前瞻性队列研究荟萃分析的伞状回顾,针对鱼类摄入与慢性病风险之间的关系进行探讨。中等质量的证据表明,鱼类摄入与较低的总死亡和心血管疾病死亡风险,以及较低的心血管疾病、抑郁症和肝癌发病风险相关,可被视为健康的动物性蛋白质饮食来源。对于证据质量被评为低和非常低的结果(如和大多数癌症的关系),还需要进一步的研究来探究,同时应考虑鱼的种类、烹调方式、地理位置、家族病史及所有潜在混杂因素的影响。
关键字
延伸阅读本研究的原文信息和链接出处,以及相关解读和评论文章。欢迎读者朋友们推荐!

Fish Consumption and the Risk of Chronic Disease: An Umbrella Review of Meta-Analyses of Prospective Cohort Studies

鱼类摄入与慢性病风险:前瞻性队列研究荟萃分析的伞状回顾

10.1093/advances/nmaa029

2020-03-24, Article

Abstract & Authors:展开

Abstract:收起
We aimed to present a comprehensive review of published meta-analyses of prospective cohort studies on the association of fish consumption and the risk of chronic disease. A systematic search was undertaken in Pubmed and Scopus to October 2019 to find meta-analyses of observational studies evaluating the association of fish consumption and the risk of chronic disease. Retrospective and cross-sectional studies and studies with unadjusted risk estimates were excluded. The summary relative risk (SRR) for each meta-analysis was recalculated by using a random-effects model. The methodological quality of included meta-analyses and the quality of the evidence were assessed by the AMSTAR and NutriGrade tools, respectively. A total of 34 meta-analyses of prospective observational studies, reporting SRRs for 40 different outcomes obtained from 298 primary prospective cohort studies, were included. Moderate-quality evidence suggested that each 100-g/d increment in fish consumption was associated with a lower risk of all-cause mortality (SRR: 0.92; 95% CI: 0.87, 0.97), cardiovascular mortality (SRR: 0.75; 95% CI: 0.65, 0.87), coronary heart disease (SRR: 0.88; 95% CI: 0.79, 0.99), myocardial infarction (SRR: 0.75; 95% CI: 0.65, 0.93), stroke (SRR: 0.86; 95% CI: 0.75, 0.99), heart failure (SRR: 0.80; 95% CI: 0.67, 0.95), depression (SRR: 0.88; 95% CI: 0.79, 0.98), and liver cancer (SRR: 0.65; 95% CI: 0.48, 0.87). For cancers of most sites, there was no significant association and the quality of the evidence was rated low and very low. In conclusion, evidence of moderate quality suggests that fish consumption is associated with a lower risk of cardiovascular disease, depression, and mortality and, therefore, can be considered as a healthy animal-based dietary source of protein. Further research is needed for outcomes for which the quality of the evidence was rated low and very low, considering types of fish consumed, different methods of cooking fish, and all potential confounding variables.

First Authors:
Ahmad Jayedi

Correspondence Authors:
Sakineh Shab-Bidar

All Authors:
Ahmad Jayedi,Sakineh Shab-Bidar

评论