关于槲皮素,你该知道的一切
  • 槲皮素是一种黄酮类化合物,具有糖苷或苷元形式,其中槲皮素-3-O-葡萄糖苷是存在于许多水果和蔬菜中的色素类物质;
  • 槲皮素糖苷可与低聚糖或多糖结合,在大肠中作为苷元被肠杆菌通过脱糖作用吸收,也可被肠道菌群的β-葡萄糖苷酶和/或乳糖水解酶水解后,在小肠被吸收;
  • 其具有抗氧化、抗炎等作用,对心血管疾病、癌症、糖尿病、神经系统疾病、肥胖、过敏哮喘和特应性疾病均具有防治效果;
  • 但其预防疾病的剂量和形式仍需进一步研究。
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文章综述了槲皮素的化学性质、吸收机制、新陈代谢、生物利用度、食物来源、生物活性以及可能促进健康的机制。虽然有相关的研究表明槲皮素具有抗氧化、抗炎等作用,对心血管疾病、癌症、糖尿病、神经系统疾病、肥胖、过敏哮喘和特应性疾病等具有抵御效果。但是根据欧洲食品安全局的说法(2011年),目前槲皮素的相关活性并不能被确定,进一步的研究被需要。
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延伸阅读本研究的原文信息和链接出处,以及相关解读和评论文章。欢迎读者朋友们推荐!

A minireview of quercetin: from its metabolism to possible mechanisms of its biological activities

关于槲皮素的综述:从代谢到可能的生物活性机制

10.1080/10408398.2019.1683810

2019-11-04, Review

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Abstract:收起
Quercetin, one of the most taken flavonoid with diet, belongs to the family of flavonols in which kaempferol and myricetin are also found. Quercetin occurs as a glycoside (with linked sugars) or as an aglycone (without linked sugars). Although quercetin has many different forms in nature, the form found in plants is quercetin-3-O-glucoside, which generally functions as a pigment that gives color to a multitude of fruits and vegetables. The recent literature has been reviewed using PubMed, Science Direct, and Embase databases. In this article, we reviewed quercetin with respect to chemical properties, absorption mechanism, metabolism, bioavailability, food sources, bioactivities, and possible health-promoting mechanisms. Quercetin is known as an antioxidant, anti-inflammatory, cardioprotective, and anti-obesity compound. It is thought to be beneficial against cardiovascular diseases, cancer, diabetes, neurological diseases, obesity, allergy asthma, and atopic diseases. Further clinical studies with large sample sizes are needed to determine the appropriate dose and form of quercetin for preventing diseases.

First Authors:
Hande Gül Ulusoy

Correspondence Authors:
Nevin Sanlier

All Authors:
Hande Gül Ulusoy,Nevin Sanlier

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