多吃鱼少吃肉,可能降低心血管疾病风险?
创作:szx 审核:szx 01月01日
  • 纳入422,791名英国受试者,中位随访8.5年,基于问卷评估受试者的饮食种类,并分析饮食种类与心血管疾病的关联;
  • 肉食者在所有受试者中的占比为94.7%,其肥胖风险高于素食者、鱼食者及家禽肉食者;
  • 相比于肉食者,鱼食者的心血管疾病发病风险显著降低,其中缺血性心脏病、心肌梗死、中风及心衰的风险均显著降低;
  • 相比于肉食者,素食者的心血管疾病发病风险降低;
  • 饮食种类与心血管疾病死亡率无显著关联。
主编推荐语
szx
European Heart Journal上发表的一项前瞻性队列研究结果,对超过40万名英国人进行近10年随访后发现,相比于肉食者,鱼食者(只摄入鱼肉,不摄入家禽肉或红肉)及素食者的总体心血管疾病发病风险显著降低,而鱼食者的缺血性心脏病、心肌梗死、中风及心衰均显著降低。
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Vegetarians, fish, poultry, and meat-eaters: who has higher risk of cardiovascular disease incidence and mortality? A prospective study from UK Biobank

素食者、鱼食者、家禽肉食者及肉食者:谁的心血管疾病发病率及死亡率更高?

10.1093/eurheartj/ehaa939

2020-12-14, Article

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Aims: To compare the incidence and mortality risk for cardiovascular diseases (CVD) [CVD and also ischaemic heart disease (IHD), myocardial infarction (MI), stroke, and heart failure (HF)] among people with different types of diets—including vegetarians, fish eaters, fish and poultry eaters, and meat-eaters—using data from UK Biobank.
Methods and results : A total of 422 791 participants (55.4% women) were included in this prospective analysis. Using data from a food frequency questionnaire, four types of diets were derived. Associations between types of diets and health outcomes were investigated using Cox proportional hazard models. Meat-eaters comprised 94.7% of the cohort and were more likely to be obese than other diet groups. After a median follow-up of 8.5 years, fish eaters, compared with meat-eaters, had lower risks of incident CVD {hazard ratios (HR): 0.93 [95% confidence intervals (CI): 0.88–0.97]}, IHD [HR: 0.79 (95% CI: 0.70–0.88)], MI [HR: 0.70 (95% CI: 0.56–0.88)], stroke [HR: 0.79 (95% CI: 0.63–0.98)] and HF [HR: 0.78 (95% CI: 0.63–0.97)], after adjusting for confounders. Vegetarians had lower risk of CVD incidence [HR: 0.91 (95% CI: 0.86–0.96)] relative to meat-eaters. In contrast, the risk of adverse outcomes was not different in fish and poultry eaters compared with meat-eaters. No associations were identified between types of diets and CVD mortality.
Conclusion: Eating fish rather than meat or poultry was associated with a lower risk of a range of adverse cardiovascular outcomes. Vegetarianism was only associated with a lower risk of CVD incidence.

First Authors:
Fanny Petermann-Rocha

Correspondence Authors:
Frederick K Ho,Carlos Celis-Morales,Jill P Pell

All Authors:
Fanny Petermann-Rocha,Solange Parra-Soto,Stuart Gray,Jana Anderson,Paul Welsh,Jason Gill,Naveed Sattar,Frederick K Ho,Carlos Celis-Morales,Jill P Pell

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