哺乳期多喝牛奶有好处,或降低儿童食物过敏风险
创作:Epi汪 审核:Epi汪 01月01日
  • 纳入瑞典出生队列中508对母婴,记录怀孕及哺乳期的母亲饮食情况,并随访后代儿童12月时过敏性疾病发生情况;
  • 其中有39名诊断为食物过敏,33名诊断为特应性湿疹,33名诊断为哮喘;
  • 在哺乳期(1个月和4个月),母亲摄入牛奶的量与新生儿食物过敏风险呈负相关;
  • 母亲在妊娠期及哺乳期摄入的乳制品、牛奶、奶酪的含量与其母乳或红细胞中的脂肪酸(C15:0、C17:0)含量呈正相关;
  • 哺乳期母亲水果摄入量与新生儿特应性湿疹的患病率呈正相关。
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Epi汪
本研究通过队列研究数据发现,母亲在哺乳期摄入较多牛奶的,其后代儿童患食物过敏的风险降低。同时,本研究中收集了多个维度的孕期/哺乳期食物摄入情况,其与儿童食物过敏、特应性疾病及哮喘等疾病存在各种不同的关联,给营养流行病学研究提供了新的思路。
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Nutrients [IF:5.717]

Maternal Intake of Cow’s Milk during Lactation Is Associated with Lower Prevalence of Food Allergy in Offspring

母亲在哺乳期摄入牛奶与新生儿食物过敏率低有关

10.3390/nu12123680

2020-11-28, Article

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Maternal diet during pregnancy and lactation may affect the propensity of the child to develop an allergy. The aim was to assess and compare the dietary intake of pregnant and lactating women, validate it with biomarkers, and to relate these data to physician-diagnosed allergy in the offspring at 12 months of age. Maternal diet during pregnancy and lactation was assessed by repeated semi-quantitative food frequency questionnaires in a prospective Swedish birth cohort (n = 508). Fatty acid proportions were measured in maternal breast milk and erythrocytes. Allergy was diagnosed at 12 months of age by a pediatrician specialized in allergy. An increased maternal intake of cow’s milk during lactation, confirmed with biomarkers (fatty acids C15:0 and C17:0) in the maternal blood and breast milk, was associated with a lower prevalence of physician-diagnosed food allergy by 12 months of age. Intake of fruit and berries during lactation was associated with a higher prevalence of atopic eczema at 12 months of age. Our results suggest that maternal diet modulates the infant’s immune system, thereby influencing subsequent allergy development.

First Authors:
Mia Stråvik

Correspondence Authors:
Ann-Sofie Sandberg

All Authors:
Mia Stråvik,Malin Barman,Bill Hesselmar,Anna Sandin,Agnes E Wold,Ann-Sofie Sandberg

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