橄榄油或有利于防治结直肠癌(综述)
创作:周旸 审核:周旸 2019年01月13日
  • 橄榄油富含的酚类物质对减少自由基、缓解炎症、免疫调节、优化肠道菌群和防控癌变具有积极作用;
  • 橄榄油可缓解炎症性肠病,其中的芹菜素、木犀草素、山楂酸、β-谷甾醇、单不饱和脂肪酸等物质分别表现出免疫调节、细胞周期调节等抗炎、抗癌作用;
  • 肠道菌群可降解橄榄油中的部分成分,产生具有抗癌作用的化合物;
  • 橄榄油及其代谢物,会改变菌群结构和功能,有助于维持健康的菌群;
  • 研究橄榄油及其代谢产物,有助于防治结直肠癌。
主编推荐语
周旸
地中海饮食表现出预防结直肠癌的作用,而橄榄油是地中海饮食的基础材料之一。本综述总结了橄榄油及其成分和代谢物的促健康作用,指出了橄榄油用于防治结直肠癌的潜在功效,对于开发防治结直肠癌的饮食干预手段具有参考价值。
关键字
延伸阅读本研究的原文信息和链接出处,以及相关解读和评论文章。欢迎读者朋友们推荐!
图片
Nutrients [IF:4.171]

Olive Oil Effects on Colorectal Cancer

橄榄油对结直肠癌的作用

10.3390/nu11010032

2018-12-23, Article

Abstract & Authors:展开

Abstract:收起
Colorectal cancer is the fourth cause of cancer-related death worldwide. A Mediterranean diet showed protective action against colorectal cancer due to the intake of different substances. Olive oil is a fundamental component of the Mediterranean diet. Olive oil is rich in high-value health compounds (such as monounsaturated free fatty acids, squalene, phytosterols, and phenols). Phenolic compounds exert favourable effects on free radicals, inflammation, gut microbiota, and carcinogenesis. The interaction between gut microbiota and olive oil consumption could modulate colonic microbial composition or activity, with a possible role in cancer prevention. Gut microbiota is able to degrade some substances found in olive oil, producing active metabolites with chemopreventive action. Further clinical research is needed to clarify the beneficial effects of olive oil and its components. A better knowledge of the compounds found in olive oil could lead to the development of nutritional supplements or chemotherapeutic agents with a potential in the prevention and treatment of colorectal cancer.

First Authors:
Antonio Maria Borzì

Correspondence Authors:
Marco Vacante

All Authors:
Antonio Maria Borzì,Antonio Biondi,Francesco Basile,Salvatore Luca,Enzo Saretto Dante Vicari,Marco Vacante

评论