饮食升糖指数及血糖负荷或增加部分慢性疾病的风险
创作:szx 审核:szx 2020年12月27日
  • 纳入18项荟萃分析(共涉及79项前瞻性队列研究)进行伞状综述,总结饮食升糖指数(GI)及血糖负荷(GL)对多种慢性疾病的影响;
  • 涉及的慢性疾病包括:不同部位的癌症、2型糖尿病、心血管疾病、抑郁、全因死亡率等;
  • 饮食GI与2型糖尿病、冠心病、结直肠癌、乳腺癌及膀胱癌的风险呈正相关,饮食GL与冠心病、2型糖尿病及中风的风险呈正相关,上述证据质量低或非常低。
主编推荐语
szx
Critical Reviews in Food Science and Nutrition上发表的一项伞状综述,总结了18项对前瞻性队列研究的荟萃分析结果,发现饮食升糖指数与2型糖尿病、冠心病、结直肠癌、乳腺癌及膀胱癌的风险呈正相关,而饮食血糖负荷与冠心病、2型糖尿病及中风的风险呈正相关。
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Dietary glycemic index, glycemic load, and chronic disease: an umbrella review of meta-analyses of prospective cohort studies

饮食升糖指数、血糖负荷及慢性疾病:对前瞻性队列研究的荟萃分析的伞状综述

10.1080/10408398.2020.1854168

2020-12-01, Review

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We aimed to present a comprehensive review of the association of dietary glycemic index (GI) and load (GL) with the risk of chronic disease. Published meta-analyses of prospective observational studies evaluating the association of dietary GI and GL with risk of chronic disease were identified by a search in PubMed and Scopus to November, 2020. Summary relative risks (SRRs) were recalculated using random-effects models. The certainty of evidence was rated by the GRADE approach. Eighteen meta-analyses of prospective cohort studies, reporting 19 SRRs for dietary GI and 17 SRRs for dietary GL were identified. There was a positive association between dietary GI and the risk of type 2 diabetes, coronary heart disease, and colorectal, breast, and bladder cancers, as well as between dietary GL and the risk of coronary heart disease, type 2 diabetes, and stroke. With regard to cancers at other sites, there was no significant association. The certainty of evidence ranged from very low to low. Although by GRADE classification no associations were rated stronger than low, they were classified as one grade higher when the NutriGrade system was used. Further research is needed to add evidence for the relation of dietary GI and GL with cancer risk.

First Authors:
Ahmad Jayedi

Correspondence Authors:
Sakineh Shab-Bidar

All Authors:
Ahmad Jayedi,Sepideh Soltani,David Jenkins,John Sievenpiper,Sakineh Shab-Bidar

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