素食如何影响孕妇的肠道菌群
创作:女巫 审核:szx
  • 母亲怀孕期间的肠道菌群与母亲和婴儿代谢状态有关;
  • 选取9名素食母亲及18名杂食母亲,分析肠道菌群差异;
  • 妊娠早期素食或杂食母亲的肠道菌群α多样性无差异,但素食者的β多样性略有下降;
  • 在素食者中有几个属的相对丰度存在差异,尤其是柯林斯氏菌属、霍尔德曼氏菌属减少,以及罗斯氏菌属和毛螺菌科的相对丰度增加;
  • 与杂食性饮食相比,素食与不同的肠道菌群相关,发酵终产物从产生混合酸的发酵向产生跟过的乙酸盐/丁酸盐改变。
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szx
孕期母亲的肠道菌群影响自身及后代的代谢状态。Nutrients上的最新一项研究发现,孕期素食改变了肠道菌群的多样性、组成及代谢产物。
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Nutrients [IF:4.546]

A Vegetarian Diet Is a Major Determinant of Gut Microbiota Composition in Early Pregnancy

素食是孕早期肠道菌群组成的关键决定因素

10.3390/nu10070890

2018-07-12, Article

Abstract & Authors:展开

Abstract:收起
The composition of the gut microbiota can be influenced by dietary composition. In pregnancy, the maternal gut microbiome has associations with maternal and infant metabolic status. There is little known regarding the impact of a vegetarian diet in pregnancy on maternal gut microbiota. This study explored the gut microbiota profile in women who were vegetarian or omnivorous in early gestation. Women were selected from participants in the Study of PRobiotics IN Gestational diabetes (SPRING) randomised controlled trial. Nine women identified as vegetarians were matched to omnivorous women in a 1:2 ratio. Microbiota analyses were performed using 16S rRNA gene amplicon sequencing and analysed using the Quantitative Insights Into Microbial Ecology (QIIME) and Calypso software tools. There was no difference in alpha diversity, but beta diversity was slightly reduced in vegetarians. There were differences seen in the relative abundance of several genera in those on a vegetarian diet, specifically a reduction in , , and increases in the relative abundances of and . In this sub-analysis of gut microbiota from women in early pregnancy, a vegetarian as compared to omnivorous diet, was associated with a different gut microbiome, with features suggesting alterations in fermentation end products from a mixed acid fermentation towards more acetate/butyrate.

First Authors:
Helen L Barrett

Correspondence Authors:
Helen L Barrett

All Authors:
Helen L Barrett,Luisa F Gomez Arango,Shelley A Wilkinson,H David McIntyre,Leonie K Callaway,Mark Morrison,Marloes Dekker Nitert

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