【营养证据】维持健康,每个人都有适合自己的生活方式
创作:药农 审核:JIAN 剑 2017年04月14日
  • 脂肪氧化是机体获得能量的关键环节,脂肪氧化的能力对于维持代谢健康极其重要。
  • 以往的研究发现,最大脂肪氧化率(MFO)存在个体差异;与心肺功能、运动情况、性别等因素有关。
  • 本文认为,MFO还与碳水化合物和脂肪的摄入量相关;这两者是独立作用的因素。
  • 如果只考虑瘦体重,则女性的MFO比男性更高(女性体脂率更高)。
  • 研究提示,在通过调节生活方式维持健康体重、改善代谢健康时,需要综合考虑性别、饮食模式、运动特点等因素。
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Dietary intake is independently associated with the maximal capacity for fat oxidation during exercise

运动中饮食与最大脂肪氧化率之间的关系

10.3945/ajcn.116.133520

2017-03-01, Article

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Background: Substantial interindividual variability exists in the maximal rate of fat oxidation (MFO) during exercise with potential implications for metabolic health. Although the diet can affect the metabolic response to exercise, the contribution of a self-selected diet to the interindividual variability in the MFO requires further clarification.Objective: We sought to identify whether recent, self-selected dietary intake independently predicts the MFO in healthy men and women.Design: The MFO and maximal oxygen uptake (V̇O2 max) were determined with the use of indirect calorimetry in 305 healthy volunteers [150 men and 155 women; mean ± SD age: 25 ± 6 y; body mass index (BMI; in kg/m(2)): 23 ± 2]. Dual-energy X-ray absorptiometry was used to assess body composition with the self-reported physical activity level (SRPAL) and dietary intake determined in the 4 d before exercise testing. To minimize potential confounding with typically observed sex-related differences (e.g., body composition), predictor variables were mean-centered by sex. In the analyses, hierarchical multiple linear regressions were used to quantify each variable's influence on the MFO.Results: The mean absolute MFO was 0.55 ± 0.19 g/min (range: 0.19-1.13 g/min). A total of 44.4% of the interindividual variability in the MFO was explained by the V̇O2 max, sex, and SRPAL with dietary carbohydrate (carbohydrate; negative association with the MFO) and fat intake (positive association) associated with an additional 3.2% of the variance. When expressed relative to fat-free mass (FFM), the MFO was 10.8 ± 3.2 mg · kg FFM(-1) · min(-1) (range: 3.5-20.7 mg · kg FFM(-1) · min(-1)) with 16.6% of the variability explained by the V̇O2 max, sex, and SRPAL; dietary carbohydrate and fat intakes together explained an additional 2.6% of the variability. Biological sex was an independent determinant of the MFO with women showing a higher MFO [men: 10.3 ± 3.1 mg · kg FFM(-1) · min(-1) (3.5-19.9 mg · kg FFM(-1) · min(-1)); women: 11.2 ± 3.3 mg · kg FFM(-1) · min(-1) (4.6-20.7 mg · kg FFM(-1) · min(-1)); P < 0.05].Conclusion: Considered alongside other robust determinants, dietary carbohydrate and fat intake make modest but independent contributions to the interindividual variability in the capacity to oxidize fat during exercise. This trial was registered at clinicaltrials.gov as NCT02070055.

First Authors:
Gareth Fletcher

Correspondence Authors:
Gareth A Wallis

All Authors:
Gareth Fletcher,Frank F Eves,Elisa I Glover,Scott L Robinson,Carlijn A Vernooij,Janice L Thompson,Gareth A Wallis

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