Nature Reviews:益生菌名词解释和框架(ISAPP共识声明)
创作:好雨 审核:好雨
  • 益生菌是“活的微生物,当给予足够量时,对宿主健康有益”;
  • 其中“核心益处”通常包含促进肠道生理和免疫系统健康两方面;
  • 潜在作用机制可在菌属中广泛存在,在大部分菌株中共存,或只在特定菌属的限定菌种中特异性调节;
  • 益生菌框架中菌和宿主间的关联包括时间关系、关系强度、特异性和一致性,剂量反应、结果可重复性、生物学合理性、替代途径、停药反应等;
  • 并探讨种属效应水平、给药方式、靶向位点、效价和调节类型等。
随着微生物组研究的飞速发展,益生菌领域在科研和市场都取得了长足进步。国际益生菌和益生元科学协会(ISAPP)在Nature Reviews Gastroenterology & Hepatology发表关于益生菌一词的范围和合理使用的共识声明。旨在促进该领域的持续发展、研究进步,并确保科学、合理地向消费者和患者传达益生菌的效用。

The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic



2014-06-10, Other

Abstract & Authors:展开

An expert panel was convened in October 2013 by the International Scientific Association for Probiotics and Prebiotics (ISAPP) to discuss the field of probiotics. It is now 13 years since the definition of probiotics and 12 years after guidelines were published for regulators, scientists and industry by the Food and Agriculture Organization of the United Nations and the WHO (FAO/WHO). The FAO/WHO definition of a probiotic—“live microorganisms which when administered in adequate amounts confer a health benefit on the host”—was reinforced as relevant and sufficiently accommodating for current and anticipated applications. However, inconsistencies between the FAO/WHO Expert Consultation Report and the FAO/WHO Guidelines were clarified to take into account advances in science and applications. A more precise use of the term 'probiotic' will be useful to guide clinicians and consumers in differentiating the diverse products on the market. This document represents the conclusions of the ISAPP consensus meeting on the appropriate use and scope of the term probiotic.

First Authors:
Colin Hill

Correspondence Authors:
Mary Ellen Sanders

All Authors:
Colin Hill,Francisco Guarner,Gregor Reid,Glenn R Gibson,Daniel J Merenstein,Bruno Pot,Lorenzo Morelli,Roberto Berni Canani,Harry James Flint,Seppo Salminen,Philip C Calder,Mary Ellen Sanders