哈尔滨医科大学:少吃晚餐,多吃早餐或对糖尿病患者有益
创作:szx 审核:szx 06月01日
  • 2003-2014年间,纳入4699名糖尿病患者,记录并计算晚餐与早餐之间摄入的能量及宏量营养素的差值;
  • 截止至2015年,共有913名患者死亡(269名为糖尿病相关,314名为心血管疾病相关);
  • 校正潜在干扰因素后,相比于晚餐与早餐差值最小的受试者,晚餐与早餐的差值最大的受试者的糖尿病相关死亡风险更高,心血管疾病相关死亡风险也更高;
  • 将晚餐摄入能量的5%用早餐替代,可分别降低4%及5%的糖尿病及心血管疾病死亡风险。
主编推荐语
szx
来自哈尔滨医科大学的李颖团队与孙长颢团队在Diabetes Care上发表的一项研究,对近5000名糖尿病患者的饮食情况进行分析,发现晚餐与早餐之间摄入的能量及宏量营养素差值越大(即晚餐吃得多,早餐吃得少),糖尿病死亡风险及心血管疾病死亡风险越高,提示糖尿病患者在一天中所摄入能量不变的情况下,应该多吃早餐,少吃晚餐。
关键字
延伸阅读本研究的原文信息和链接出处,以及相关解读和评论文章。欢迎读者朋友们推荐!
图片
Diabetes Care [IF:16.019]

The Association of Energy and Macronutrient Intake at Dinner Versus Breakfast With Disease-Specific and All-Cause Mortality Among People With Diabetes: The U.S. National Health and Nutrition Examination Survey, 2003–2014

早餐或晚餐的能量与宏量营养素摄入与糖尿病患者的疾病特异性死亡率及全因死亡率的关联

10.2337/dc19-2289

04-04, Article

Abstract & Authors:展开

Abstract:收起
OBJECTIVE: This study aims to evaluate the association of energy and macronutrient intake at dinner versus breakfast with disease-specific and all-cause mortality in people with diabetes.
RESEARCH DESIGN AND METHODS: A total of 4,699 people with diabetes who enrolled in the National Health and Nutrition Examination Survey from 2003 to 2014 were recruited for this study. Energy and macronutrient intake was measured by a 24-h dietary recall. The differences (Δ) in energy and macronutrient intake between dinner and breakfast (Δ = dinner − breakfast) were categorized into quintiles. Death information was obtained from the National Death Index until 2015. Cox proportional hazards regression models were developed to evaluate the survival relationship between Δ and diabetes, cardiovascular disease (CVD), and all-cause mortality.
RESULTS: Among the 4,699 participants, 913 deaths, including 269 deaths due to diabetes and 314 deaths due to CVD, were documented. After adjustment for potential confounders, compared with participants in the lowest quintile of Δ in terms of total energy and protein, participants in the highest quintile were more likely to die due to diabetes (hazard ratio [HR]Δenergy 1.92, 99% CI 1.08–3.42; HRΔprotein 1.92, 99% CI 1.06–3.49) and CVD (HRΔenergy 1.69, 99% CI 1.02–2.80; HRΔprotein 1.96, 99% CI 1.14–3.39). The highest quintile of Δtotal fat was related to CVD mortality (HR 1.67, 99% CI 1.01–2.76). Isocalorically replacing 5% of total energy at dinner with breakfast was associated with 4% and 5% lower risk of diabetes (HR 0.96, 95% CI 0.94–0.98) and CVD (HR 0.95, 95% CI 0.93–0.97) mortality, respectively.
CONCLUSIONS: Higher intake of energy, total fat, and protein from dinner than breakfast was associated with greater diabetes, CVD, and all-cause mortality in people with diabetes.

First Authors:
Tianshu Han

Correspondence Authors:
Changhao Sun,Ying Li

All Authors:
Tianshu Han,Jian Gao,Lihong Wang,Chao Li,Lu Qi,Changhao Sun,Ying Li

评论