饮食如何影响菌群与心血管疾病(综述)
  • 肠道菌群组成及其在肠道微环境中的初级和次级代谢产物与心脏代谢性疾病风险相关;
  • 饮食可以改变肠道环境和菌群,并为菌群代谢提供底物,因此评估不同类型的饮食模式与疾病之间的关联意义重大;
  • 地中海式饮食指多吃水果蔬菜及海鲜坚果等清淡营养的食物,临床追踪试验也发现地中海式饮食或者素食主义有助于降低心脏代谢性疾病发生;
  • 这种饮食方式有助于产生短链脂肪酸,减少三甲胺及次级胆酸生成;
  • 健康饮食对于预防心血管疾病非常重要。
主编推荐语
mildbreeze
Journal of Nutrition近期发表一篇小综述,主要介绍了地中海饮食和素食两种饮食模式,对肠道菌群、菌群代谢物和心血管疾病的影响,值得关注。
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Dietary Patterns Affect the Gut Microbiome—The Link to Risk of Cardiometabolic Diseases

饮食模式影响肠道菌群--与心血管代谢疾病风险的联系

10.1093/jn/nxy141

2018-08-31, Article

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Abstract:收起
Clusters of bacterial species within the gut microenvironment, or gut enterotype, have been correlated with cardiometabolic disease risk. The metabolic products and metabolites that bacteria produce, such as short-chain fatty acids, secondary bile acids, and trimethylamine, may also affect the microbial community and disease risk. Diet has a direct impact on the gut microenvironment by providing substrates to and promoting the colonization of resident bacteria. To date, few dietary patterns have been evaluated for their effect on the gut microbiome, but the Mediterranean diet and Vegetarian diets have shown favorable effects for both the gut microbiome and cardiometabolic disease risk. This review examines the gut microbiome as a mediator between these dietary patterns and cardiometabolic disease risk.

First Authors:
Alyssa M Tindall

Correspondence Authors:
Penny M Kris-Etherton

All Authors:
Alyssa M Tindall,Kristina S Petersen,Penny M Kris-Etherton

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