JAMA:想不胖?睡好,少吃,管好生物钟!
创作:szx 审核:szx 2017年07月30日
  • 生物钟基因突变的小鼠表现出肥胖、代谢综合征、睡眠减少、进食时间改变;
  • 同样食用高脂饮食,进食时间异常的小鼠比进食时间正常的小鼠体重增加更多;
  • 昼夜节律紊乱的人超重及糖尿病风险更高;
  • 睡眠不足对糖耐受及体重有不利影响,并增加饥饿感,恢复睡眠时间可逆转上述症状;
  • 改善睡眠及限时进食在动物实验及初步人类研究中展现出重置生物钟并恢复健康代谢的潜能;
  • 一项人体初步试验发现,恢复正常进食时间可帮助减重,并改善睡眠质量。
主编推荐语
蓝灿辉 | 热心肠先生
这是JAMA发出的一篇小文章,介绍针对动物和人的生物钟重置如何改善代谢健康,结论可能并不新颖,很多人或者也知道,但这样的文章除了看其后面的科学研究,更重要的还是再次提醒健康的饮食和生活规律,很重要!强烈推荐!
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JAMA [IF:45.54]

Resetting the Circadian Clock Might Boost Metabolic Health

重置生物钟可能促进代谢健康

10.1001/jama.2017.0653

2017-04-04, News Item

Abstract & Authors:展开

Abstract:收起
Consider a quarterback’s passing game: throw the ball too soon and his receiver isn’t in place; throw the ball too late and he risks getting sacked. Either way, he isn’t in sync with his team to move the ball up field. A similar scenario may occur when eating and sleeping habits are out of sync with the body’s circadian clock, leading to metabolic disturbances. Over the past 20 years, scientists have assembled a clearer picture of the circadian clocks that keep human physiology tuned to the 24-hour light-dark cycle. Now, the basic science is giving way to human studies that reveal how a person’s sleeping habits, eating patterns, and diet may desynchronize the body’s clocks and contribute to metabolic problems like obesity or diabetes.

First Authors:
Bridget M Kuehn

Correspondence Authors:
Bridget M Kuehn

All Authors:
Bridget M Kuehn

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