间歇性能量限制可有效改善体重及部分健康指标
创作:szx 审核:szx 2020年05月24日
  • 纳入17项RCT(至少持续12周,共涉及1328名超重或肥胖受试者)进行荟萃分析,对比间歇性能量限制(IER)与对照饮食对人体测量学指标及疾病标志物的影响;
  • 与正常饮食相比,IER显著降低了体重、腰围、脂肪量、甘油三酯及收缩压,但对LDL胆固醇、空腹血糖、糖化血红蛋白无显著影响;
  • IER与持续性能量限制对体重、脂肪量及其它各项指标有着相似的降低作用。
主编推荐语
szx
Critical Reviews in Food Science and Nutrition上发表的一项荟萃分析结果,对17项RCT研究的结果进行总结:间歇性能量限制可有效降低超重/肥胖者的体重、腰围、脂肪量、甘油三酯及收缩压,且改善作用与持续性能量限制类似。
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Impact of intermittent energy restriction on anthropometric outcomes and intermediate disease markers in patients with overweight and obesity: systematic review and meta-analyses

间歇性能量限制对超重及肥胖者的人体测量学结局及中间疾病标志物的影响:系统性综述与荟萃分析

10.1080/10408398.2020.1757616

2020-05-02, Review

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Abstract:收起
This systematic review aims to investigate the effects of intermittent energy restriction (IER) on anthropometric outcomes and intermediate disease markers. A systematic literature search was conducted in three electronic databases. Randomized controlled trials (RCTs) were included if the intervention lasted ≥12 weeks and IER was compared with either continuous energy restriction (CER) or a usual diet. Random-effects meta-analysis was performed for eight outcomes. Certainty of evidence was assessed using GRADE. Seventeen RCTs with 1328 participants were included. IER in comparison to a usual diet may reduce body weight (mean difference [MD]: −4.83 kg, 95%-CI: −5.46, −4.21; n = 6 RCTs), waist circumference (MD: −1.73 cm, 95%-CI: −3.69, 0.24; n = 2), fat mass (MD: −2.54 kg, 95%-CI: −3.78, −1.31; n = 6), triacylglycerols (MD: −0.20 mmol/L, 95%-CI: −0.38, −0.03; n = 5) and systolic blood pressure (MD: −6.11 mmHg, 95%-CI: −9.59, −2.64; n = 5). No effects were observed for LDL-cholesterol, fasting glucose, and glycosylated-hemoglobin. Both, IER and CER have similar effect on body weight (MD: −0.55 kg, 95%-CI: −1.01, −0.09; n = 13), and fat mass (MD: −0.66 kg, 95%-CI: −1.14, −0.19; n = 10), and all other outcomes. In conclusion, IER improves anthropometric outcomes and intermediate disease markers when compared to a usual diet. The effects of IER on weight loss are similar to weight loss achieved by CER.

First Authors:
Lukas Schwingshackl

Correspondence Authors:
Lukas Schwingshackl

All Authors:
Lukas Schwingshackl,Jasmin Zähringer,Kai Nitschke,Gabriel Torbahn,Szimonetta Lohner,Tilman Kühn,Luigi Fontana,Nicola Veronese,Christine Schmucker,Joerg J Meerpohl

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